Bioingred Tech S.A.S - Laboratory provider of efficacy and safety studies for natural ingredients (CO12-E1-1)

Procurement No: 100005260

Description: Bioingred Tech S.A.S - Laboratory provider of efficacy and safety studies for natural ingredients (CO12-E1-1)

Scope 1: Safety evaluation
Test Method Number of ingredients to evaluate Number of concentrations per ingredient Volunteers per concentration
1 Non-irritating test Patch test 7 2 Min. 10
1 Eye irritation HET-CAM or equivalent 7 1 n.r.
1 Cell cytotoxicity test MTT 7 8 n.r

Scope 2: In vitro efficacy evaluation
Test Method Number of ingredients to evaluate Number of concentrations per ingredient
2 In vitro Anti-aging test Elastine and hyaluronic acid synthesis (human fibroblast) 1 1
2 In vitro SPF UVA-UVB spectrophotometer 2 1
2 In vitro Anti-pollution In vitro free radicals scavenging with exposed cells to urban dust 2 4
2 In vitro skin barrier regeneration In vitro endothelial cell regeneration (HUVEC) 1 8
2 In vitro tyrosinase inhibition Cell tyrosinase inhibition 1 6
2 In vitro antioxidant activity In vitro free radicals scavenging cell antioxidant test 7 6

Scope 3: In vivo efficacy evaluation
Test Method Number of ingredients Number of concentrations per ingredient Volunteers
3 In Vivo Elasticity and firmness Cutometer 1 1 Min. 20
3 In vivo Hair Detangling Evaluation Combing test 2 1 Min. 20
3 In vivo Hair Moisturizing Efficacy Tewameter 2 1 Min. 20
3 In vivo Microcirculation Improvement Thermography 1 1 Min. 20
3 In vivo Whitening Efficacy Image analysis (Mexameter) 1 1 Min. 20
3 In vivo cell renewal evaluation Corneometer 1 1 Min. 20
3 In vivo Skin Moisturizing Efficacy Corneometer 5 1 Min. 20