Innovative single-cell RNA-seq kit to detect the rarer and more significant cellular genomic expressions: DEEP-IN-CELL

Programme(s): HORIZON.3.1 - The European Innovation Council (EIC)

Topic(s): HORIZON-EIC-2022-ACCELERATOROPEN-01 - EIC Accelerator Open

Call for proposal: HORIZON-EIC-2022-ACCELERATOR-01

Funding Scheme: EIC-ACC - EIC-ACC

Grant agreement ID: 190178154

Objective:

This project will develop and perform the industrial scale-up of a game-changing scRNA-seq tool named DEEP-IN-CELL. This solution, in a kit format plus a cloud software analysis suite, will use multiple barcode beads per cell to greatly improve the cell capture rate (over 80% versus 25-50% with current technologies) and the percentage of cell contents captured (2-3 times higher than the current levels of 10-20%). Proteomic profiles, specific genes, and cell types will also be targeted.
With high sensitivity to rare events, DEEP-IN-CELL will overcome the current limitations in single-cell research and expand the applications of scRNA-seq to important new clinical opportunities.
The product will reach the international single-cell research market and is expected to generate sales exceeding €100M by 2026. Scipio will become the uncontested provider of leading single-cell RNA-seq kits, thereby establishing a new standard and new best practices in single-cell research.