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18 September 2025
PROPOSAL NUMBERS
Call HORIZON-CL6-2025-01 has closed on 17/09/2025
515 proposals have been submitted.
The breakdown per topic is:
·HORIZON-CL6-2025-01-ZEROPOLLUTION-07 : 16
Evaluation results are expected to be communicated in January 2026.
11 June 2025
Please note that due to a technical issue, during the first days of publication of this call, the topic page did not display the description of the corresponding destination. This problem is now solved. In addition to the information published in the topic page, you can always find a full description of the 7 destinations (Biodiversity and ecosystem services; Fair, healthy and environment-friendly food systems from primary production to consumption; Circular economy and bioeconomy sectors; Clean environment and zero pollution; Land, ocean and water for climate action; Resilient, inclusive, healthy and green rural, coastal and urban communities; Innovative governance, environmental observations and digital solutions in support of the Green Deal) that are relevant for the call in the Work Programme 2025 part for “Food, Bioeconomy, Natural Resources, Agriculture and Environment”. Please select from the work programme the destination relevant to your topic and take into account the description and expected impacts of that destination for the preparation of your proposal.
TOPIC ID: HORIZON-CL6-2025-01-ZEROPOLLUTION-07
Type of grant: Call for proposals
General information
Programme:
Call: Cluster 6 Call 01 - single stage (HORIZON-CL6-2025-01)
Type of action: HORIZON-IA HORIZON Innovation Actions
Type of MGA: HORIZON Action Grant Budget-Based [HORIZON-AG]
Status: Open for submission
Deadline model: single-stage
Opening Date: 06 May 2025
Deadline dates: 17 September 2025 17:00 (Brussels time)
Topic description
Expected Outcome:
In line with the European Green Deal priorities, the zero pollution action plan, chemical strategy for sustainability, farm to fork strategy for a fair, healthy and environment‑friendly food system, the biodiversity strategy for 2030, notably its objective of reducing pollution, and the EU’s climate ambition for 2030 and 2050, the successful proposal will support R&I to reduce pollution coming from food systems (and eventually stop it). This will contribute to the transformation of food systems to deliver co‑benefits for climate (mitigation and adaptation), biodiversity, environmental sustainability and circularity, sustainable healthy nutrition and safe food, food poverty reduction, empowerment of communities, and thriving businesses.
Project results are expected to contribute to all of the following expected outcomes:
Scope:
Food systems, on the one hand, are a source of pollution and, on the other hand, suffer from the consequences of pollution. Moving towards zero pollution food systems can therefore contribute to building the resilience of food systems and the natural ecosystems on which they depend. Contaminants have been accumulating in food products, whether due to food being in contact with specific materials at various stages of the food supply chain, such as food processing plants, packaging, or in agriculture with contaminated soils, air and water.
In the context of the Industrial and Livestock Rearing Emissions Directive and the relevant Best Available Techniques (BAT) conclusions for the food, drink and milk industries, some data are already available. However, there are currently several knowledge gaps when it comes to emerging and/or less known pollutants, and their cocktail effects on the environment and human health.
Some activities of the food and drink industries can lead to soil, water and air pollution, which can, in turn, adversely affect food safety, biodiversity and human health. This pollution can take many forms: plastics (including micro- and nano-plastics), food packaging, persistent chemicals, light, noise, odour, etc. There are significant regional differences in the impact of environmental pollution, depending on the type of pollutant. While European and national strategies remain important to reducing pollution, international cooperation is key to ensure that efficient and impactful measures are put in place to protect our oceans and inland waters, ecosystems, biodiversity and health.
The proposals are expected to:
This topic contributes to the European Green Deal priorities, the zero pollution action plan, chemical strategy for sustainability, farm to fork strategy for a fair, healthy and environment‑friendly food system, the biodiversity strategy for 2030, notably its objective of reducing pollution, and the EU’s climate ambition for 2030 and 2050. The successful proposal will contribute to the transformation of food systems to deliver co‑benefits for climate (mitigation and adaptation), biodiversity, environmental sustainability and circularity, sustainable healthy nutrition and safe food, food poverty reduction, empowerment of communities, and thriving businesses.
For any activities on depollution to achieve zero pollution in large industrial installations and contribute to the climate ambition, please refer to the Innovation Centre for Industrial Transformation and Emissions (INCITE) (https://innovation-centre-for-industrial-transformation.ec.europa.eu/).
Proposals must implement the multi-actor approach by involving a wide range of food system actors and conducting multi-disciplinary research (including on environmental science and biodiversity). International cooperation is strongly encouraged.
Where relevant, activities should build and expand on the results of past and ongoing research projects. Projects should have a clear plan as to how they will collaborate with other projects selected under this topic and any other relevant topic or relevant EU partnerships. They should participate in joint activities, workshops, focus groups or social labs, and common communication and dissemination activities, and show potential for upscaling. Applicants should plan the necessary budget to cover these activities.
described in Annex A and Annex E of the Horizon Europe Work Programme General Annexes.
Proposal page limits and layout: described in Part B of the Application Form available in the Submission System.
described in Annex B of the Work Programme General Annexes.
A number of non-EU/non-Associated Countries that are not automatically eligible for funding have made specific provisions for making funding available for their participants in Horizon Europe projects. See the information in the Horizon Europe Programme Guide.
The following additional eligibility criteria apply: The proposals must apply the multi-actor approach. See definition of the multi-actor approach in the introduction to this work programme part.
described in Annex B of the Work Programme General Annexes.
described in Annex C of the Work Programme General Annexes.
are described in Annex D of the Work Programme General Annexes.
are described in Annex F of the Work Programme General Annexes and the Online Manual.
described in Annex F of the Work Programme General Annexes.
described in Annex G of the Work Programme General Annexes.
described in the [specific topic of the Work Programme]
Application form templates — the application form specific to this call is available in the Submission System
Standard application form (HE RIA, IA)
Evaluation form templates — will be used with the necessary adaptations
Standard evaluation form (HE RIA, IA)
Guidance
HE Programme Guide
Model Grant Agreements (MGA)
HE MGA
Call-specific instructions
HE Main Work Programme 2025 – 1. General Introduction
HE Main Work Programme 2025 – 9. Food, Bioeconomy, Natural Resources, Agriculture and Environment
HE Main Work Programme 2025 – 14. General Annexes
HE Programme Guide
HE Framework Programme 2021/695
HE Specific Programme Decision 2021/764
EU Financial Regulation 2024/2509
Rules for Legal Entity Validation, LEAR Appointment and Financial Capacity Assessment
EU Grants AGA — Annotated Model Grant Agreement
Funding & Tenders Portal Online Manual
Funding & Tenders Portal Terms and Conditions
Funding & Tenders Portal Privacy Statement
Start submission
To access the Electronic Submission Service, please click on the submission-button next to the type of action and the type of model grant agreement that corresponds to your proposal. You will then be asked to confirm your choice, as it cannot be changed in the submission system. Upon confirmation, you will be linked to the correct entry point.
To access existing draft proposals for this topic, please login to the Funding & Tenders Portal and select the My Proposals page of the My Area section.
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Please read carefully all provisions below before the preparation of your application.
Online Manual is your guide on the procedures from proposal submission to managing your grant.
Horizon Europe Programme Guide contains the detailed guidance to the structure, budget and political priorities of Horizon Europe.
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CEN-CENELEC Research Helpdesk and ETSI Research Helpdesk – the European Standards Organisations advise you how to tackle standardisation in your project proposal.
The European Charter for Researchers and the Code of Conduct for their recruitment – consult the general principles and requirements specifying the roles, responsibilities and entitlements of researchers, employers and funders of researchers.
Partner Search help you find a partner organisation for your proposal.

Horizon Europe will incorporate research and innovation missions to increase the effectiveness of funding by pursuing clearly defined targets.
The Commission has engaged policy experts to develop studies, case studies and reports on how a mission-oriented policy approach will work.
Mission areas
5 mission areas have been identified, each with a dedicated mission board and assembly. The board and assembly help specify, design and implement the specific missions which will launch under Horizon Europe in 2021.
Features all the components, activities, and processes related to food production, processing, safety, and access, as well as initiatives that support livelihoods and income generation for individuals and communities.
Includes initiatives aimed at reducing environmental pollution and improving the collection, treatment, and disposal of waste.