Experimental medicine invited stage two application

Objectives: The Medical Research Council's (MRC) Experimental Medicine Grant provides funds to investigate human disease mechanisms, progression, and treatment. This initiative targets academically-led projects involving mechanistic hypotheses and experimental interventions in humans, encouraging broad engagement across various disease areas and interventions. Applicants can apply for any amount needed, with projects funded at 80% of the full economic cost. Emphasis is on generating scientific insights that enable the future development of novel therapeutics or diagnostics, focusing on changing disease pathways and addressing identified gaps in human pathophysiology understanding. Projects require a clear path to clinical impact, indicative of high scientific merit and innovation potential.